If you're looking for a place to get away, look no further than East Prairie. Whether you're planning to stay for a night or for the week, the area around East Prairie has accommodations to fit every need. Search for hotels in East Prairie with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all East Prairie hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best East Prairie hotel deals are here with our lowest price guarantee.
Hotels in East Prairie
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Where to stay in East Prairie?

Quality Inn Charleston - Sikeston
Quality Inn Charleston - Sikeston
6.8 out of 10, (374)
The price is $73
$81 total
includes taxes & fees
Apr 13 - Apr 14
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top landmarks in East Prairie
Big Oak Tree State Park
Big Oak Tree State Park is 10.3 mi (16.6 km) from central East Prairie, why not stop by during your stay.
Learn more about East Prairie
East Prairie is well-known for its attractions such as Big Oak Tree State Park and Mississippi River.
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