Hotels in Santa María Tlalixtac

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Where to stay in Santa María Tlalixtac?

Learn more about Santa María Tlalixtac

Take in the local culture with a visit to María Sabina Museum nearby during your stay.

Frequently asked questions

Can I book a refundable hotel in Santa María Tlalixtac?
If you want the flexibility to change your travel plans to Santa María Tlalixtac, most accommodations offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Santa María Tlalixtac be like during my vacation?
Santa María Tlalixtac is a great place to visit any time of year with an average temperature of 71°F during the coldest months.
Why should I book my Santa María Tlalixtac hotel with Hotels.com?
There are lots of reasons to book your Santa María Tlalixtac trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.