Hotels in Mytilene

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Where to stay in Mytilene?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Mytilene

Learn more about Mytilene

Notable for its seaside, Mytilene features attractions such as Port of Mytilene and Mytilini Castle.

Frequently asked questions

What hotels do travelers like in Mytilene?
Theofilos Paradise Boutique Hotel and Heliotrope Hotels are a couple of accommodations that are popular with guests.
Where can I get free parking at my hotel in Mytilene?
These hotels offer the perk of free parking: Theofilos Paradise Boutique Hotel and Heliotrope Hotels.
Can I book a refundable hotel in Mytilene?
If you need the flexibility to change your travel plans to Mytilene, most properties offer refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Mytilene if I'm looking for a cheap accommodation?
Porto Lesvos is an accommodation you might want to consider that’ll save you money.
Where can I stay in Mytilene if I want a vacation home instead of a hotel?
You’ll find 11 vacation homes on our site. You can also book one of 18 apartments or 17 villas.
What will the weather in Mytilene be like during my vacation?
The warmest months in Mytilene are usually August and July with an average temp of 77°F. January and February are the chilliest months when the average temp is 52°F. The rainiest months are January and December.
Why should I book my Mytilene hotel through Hotels.com?
There are plenty of reasons to book your Mytilene travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.