Photo by Caroline Nunez

Hotels in Mayesville

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March 2025
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Where to stay in Mayesville?

1912 Bed and Breakfast
Front of property

1912 Bed and Breakfast

3.5 star property
10.0 out of 10, Exceptional, (247)
The price is $123
$138 total
includes taxes & fees
Jan 26 - Jan 27
1912 Bed and Breakfast
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mayesville

The region around Mayesville is home to attractions such as Crystal Lakes Golf Course and O'Donnell House.

See all hotels in Mayesville
Somewhere in rural South Carolina off a back road to my hometown. Saw the sunflower field and had to stop.
Photo by Caroline Nunez
Open Photo by Caroline Nunez

Frequently asked questions

What hotels do travelers like in Mayesville?
Guests like Hyatt Place Sumter / Downtown, Super 8 by Wyndham Sumter and Mount Vernon Inn.
Can I book a refundable accommodation in Mayesville?
If you need the flexibility to change your travel plans to Mayesville, most hotels offer refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Mayesville be like during my vacation?
July and August are typically the warmest months in Mayesville when the average temp is 79°F. January and February are the coldest months when the average temperature is 50°F. August and July are the months with the most rain.
Why should I book my Mayesville hotel through Hotels.com?
There are lots of reasons to book your Mayesville trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.