Hotels in Santa Isabel

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March 2025
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Where to stay in Santa Isabel?

Don Antonio Hotel
Interior detail

Don Antonio Hotel

3.0 star property
9.2 out of 10, Wonderful, (9)
The price is $65
$68 total
includes taxes & fees
Jan 24 - Jan 25
Don Antonio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Santa Isabel

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Frequently asked questions

Can I book a refundable accommodation in Santa Isabel?
If you want the flexibility to change your travel plans to Santa Isabel, most properties offer refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Santa Isabel be like during my visit?
Santa Isabel is a great place to visit to enjoy the sunshine any time of year with an average temp of 74°F.
Why should I book my Santa Isabel accommodation with Hotels.com?
There are lots of reasons to book your Santa Isabel trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.