Hotels in Santa Isabel

your current months are January, 2025 and February, 2025.
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February 2025

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Where to stay in Santa Isabel?

Desert Inn Mexicali
Restaurant

Desert Inn Mexicali

3.0 star property
9.4 out of 10, Exceptional, (3)
The price is $35
$42 total
includes taxes & fees
Dec 19 - Dec 20
Desert Inn Mexicali
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santa Isabel

Mexicali Border Port I

After visiting Mexicali Border Port I, make a plan to see the other sights and activities in Mexicali. While in this family-friendly area, you can savor the top-notch restaurants.

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Mexicali Border Port I

Learn more about Santa Isabel

The region around Santa Isabel is home to attractions such as Mexicali Border Port I and Palenque Fex.

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Frequently asked questions

Can I book a refundable hotel in Santa Isabel?
If you need the flexibility to change your plans to Santa Isabel, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Santa Isabel be like during my trip?
July and August are typically the warmest months in Santa Isabel when the average temp is 93°F. December and January are the coldest months when the average temperature is 61°F. August and January are the months with the most rain.
Why should I book my Santa Isabel hotel through Hotels.com?
There are lots of reasons to book your Santa Isabel trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.