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Hotels in Cape Girardeau

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Where to stay in Cape Girardeau?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Cape Girardeau

Frequently asked questions

What hotels do travelers recommend in Cape Girardeau?
Can I book a refundable hotel in Cape Girardeau?
If you need the flexibility to change your travel plans to Cape Girardeau, most accommodations offer refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in Cape Girardeau if I'm looking for an affordable accommodation?
Where can I stay in Cape Girardeau if I want a vacation rental instead of a hotel?
If you want a good alternative to a hotel, look over our selection of 23 vacation homes. In addition, you can choose from 14 apartments.
What will the weather in Cape Girardeau be like during my vacation?
July and August are typically the warmest months in Cape Girardeau when the average temp is 76°F. January and February are the coldest months when the average temperature is 40°F. April and March are the months with the most rain.
Why should I book my Cape Girardeau hotel through Hotels.com?
There are lots of reasons to book your Cape Girardeau trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.