Hotels in Orangeburg
Free cancellation options if plans change
Earn rewards on every night you stay
Save more with Member Prices
Check prices for these dates
Where to stay in Orangeburg?

Baymont by Wyndham Orangeburg North
Baymont by Wyndham Orangeburg North
Comfort Inn & Suites Orangeburg
Comfort Inn & Suites Orangeburg
SpringHill Suites by Marriott Orangeburg
SpringHill Suites by Marriott Orangeburg
Quality Inn & Suites Orangeburg
Quality Inn & Suites Orangeburg
Travelodge by Wyndham Orangeburg
Travelodge by Wyndham Orangeburg
Super 8 by Wyndham, Orangeburg
Super 8 by Wyndham, Orangeburg
Orangeburg Inn & Suites
Orangeburg Inn & Suites
Tru by Hilton Orangeburg
Tru by Hilton Orangeburg
Southern Lodge 601
Southern Lodge 601
Sleep Inn Orangeburg
Sleep Inn Orangeburg
Holiday Inn Express & Suites Orangeburg by IHG
Holiday Inn Express & Suites Orangeburg by IHG
Hampton Inn & Suites Orangeburg
Hampton Inn & Suites Orangeburg
Spark by Hilton Orangeburg
Spark by Hilton Orangeburg
Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott Orangeburg
Suburban Studios Orangeburg
Suburban Studios Orangeburg
Crown Inn By Oyo Orangeburg Hwy 301
Crown Inn By Oyo Orangeburg Hwy 301
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott Santee
Baymont by Wyndham Santee
Baymont by Wyndham Santee
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95
Peach Tree Inn
Peach Tree InnGet last-minute hotel deals in Orangeburg and save more


Check out pet-friendly hotels in Orangeburg

You may also like hotels with pools in Orangeburg

Go beyond your typical stay in Orangeburg
Top landmarks in Orangeburg
Orangeburg and related destinations
Between moss-draped oaks, Orangeburg reveals its civil rights legacy at the Cecil Williams Museum, where powerful photographs tell stories of struggle and triumph. Edisto Memorial Gardens offers a peaceful retreat with vibrant roses and winding waterways perfect for afternoon contemplation. The historic campuses of South Carolina State and Claflin universities anchor the city with scholarly gravitas and architectural beauty. Sports enthusiasts can catch thrilling games at the Smith-Hammond-Middleton Memorial Center, where local passion fills the stands. For a cosmic perspective, the I.P. Stanback Museum & Planetarium combines art with astronomy in unexpected ways. The town's trading post origins from 1704 have evolved into a place where history feels tangibly present at every corner.

Check out reviews of Orangeburg hotels guests love







































































































































