I love going to the Travel Hub, as it's a relaxing guesthouse, with several social areas, and the staff are fantastic and very engaging. I have frequented there over the years, primarily because of this. It is a short walk from Pasar Seni sky train station, which is only one stop from KL Sentral - the main junction station, and in the heart of Chinatown.
There is a bit of poverty in the area, which may be a shock to those unused to seeing it, but it is otherwise a safe neighbourhood. Talk with the staff if worried and they will gladly help you out.