Hotels in Santa Cruz
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Where to stay in Santa Cruz?
Sun Hotel
Sun Hotel
3.5 star property
Santa Cruz
8.4 out of 10, Very Good, (331)
8.4/10
Very Good
(331)
The price is $90
$90
$90 total
Dec 19 - Dec 20
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel
5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (211)
9.0/10
Wonderful
(211)
The price is $111
$111
$111 total
Dec 26 - Dec 27
Novotel Santa Cruz De La Sierra
Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2 out of 10, Wonderful, (104)
9.2/10
Wonderful
(104)
The price is $99
$99
$99 total
Dec 27 - Dec 28
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (347)
9.0/10
Wonderful
(347)
The price is $125
$125
$125 total
Dec 23 - Dec 24
Cosmopolitano Hotel Boutique
Cosmopolitano Hotel Boutique
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (122)
9.2/10
Wonderful
(122)
Camino Real Hotel
Camino Real Hotel
4.5 star property
Santa Cruz
8.8 out of 10, Excellent, (407)
8.8/10
Excellent
(407)
The price is $180
$180
$180 total
Dec 25 - Dec 26
Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (81)
9.2/10
Wonderful
(81)
The price is $140
$140
$140 total
Dec 18 - Dec 19
Hotel BY Armonia SCZ
Hotel BY Armonia SCZ
3.0 star property
Santa Cruz
8.4 out of 10, Very Good, (7)
8.4/10
Very Good
(7)
Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel Equipetrol
3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (81)
9.0/10
Wonderful
(81)
The price is $39
$39
$39 total
Dec 18 - Dec 19
HOTEL OSHO
HOTEL OSHO
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (34)
9.2/10
Wonderful
(34)
The price is $50
$50
$50 total
Dec 18 - Dec 19
Hotel Cortez
Hotel Cortez
3.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (123)
9.2/10
Wonderful
(123)
The price is $126
$126
$126 total
Dec 24 - Dec 25
Ibis Santa Cruz DE LA Sierra
Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6 out of 10, Exceptional, (74)
9.6/10
Exceptional
(74)
The price is $38
$38
$38 total
Dec 22 - Dec 23
Mirador del Cielo
Mirador del Cielo
3.0 star property
Santa Cruz
The price is $25
$25
$25 total
Dec 18 - Dec 19
Posada Express Fast Check
Posada Express Fast Check
3.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (2)
10/10
Exceptional
(2)
The price is $40
$40
$44 total
Dec 18 - Dec 19
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
Hampton by Hilton Santa Cruz/Equipetrol, Bolivia
4.5 star property
Santa Cruz
9.2 out of 10, Wonderful, (256)
9.2/10
Wonderful
(256)
The price is $74
$74
$74 total
Dec 20 - Dec 21
Equipetrol Suites Apart Hotel
Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.4 out of 10, Very Good, (7)
8.4/10
Very Good
(7)
The price is $41
$41
$41 total
Jan 16 - Jan 17, 2026
Casa Por Temporadas
Casa Por Temporadas
2.0 star property
Santa Cruz
10.0 out of 10, Exceptional, (1)
10/10
Exceptional
(1)
The price is $86
$86
$86 total
Dec 18 - Dec 19
Urban Suites
Urban Suites
3.0 star property
Santa Cruz
The price is $55
$55
$55 total
Dec 18 - Dec 19
Hotel G
Hotel G
3.5 star property
Santa Cruz
7.8 out of 10, Good, (105)
7.8/10
Good
(105)
The price is $57
$57
$57 total
Jan 12 - Jan 13, 2026
Hotel Continental Park
Hotel Continental Park
3.0 star property
Santa Cruz
8.8 out of 10, Excellent, (25)
8.8/10
Excellent
(25)
The price is $69
$69
$69 total
Dec 18 - Dec 19
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Santa Cruz
Showing deals for:Dec 26 - Dec 28
Image gallery for Novotel Santa Cruz De La Sierra
VIP Access
Novotel Santa Cruz De La Sierra
5.0 star property
Santa Cruz
9.2/10Wonderful (104 reviews)
Member Price available
$99 nightly
Price is $199
$199
Image gallery for Swissôtel Santa Cruz De La Sierra
Swissôtel Santa Cruz De La Sierra
4.5 star property
Santa Cruz
9.2/10Wonderful (81 reviews)
Member Price available
$140 nightly
Price is $281
$281
Image gallery for HOTEL OSHO
HOTEL OSHO
3.5 star property
Santa Cruz
9.2/10Wonderful (34 reviews)
10% off
$50 nightly
Price is $100
$100
Image gallery for Apart Hotel Toborochi
Apart Hotel Toborochi
3.0 star property
Santa Cruz
8.8/10Excellent (60 reviews)
15% off
$64 nightly
Price is $128
$128
Image gallery for Ibis Santa Cruz DE LA Sierra
Ibis Santa Cruz DE LA Sierra
3.0 star property
Santa Cruz
9.6/10Exceptional (74 reviews)
Member Price available
$42 nightly
Price is $84
$84
Image gallery for Equipetrol Suites Apart Hotel
VIP Access
Equipetrol Suites Apart Hotel
2.5 star property
Santa Cruz
8.4/10Very Good (7 reviews)
20% off
$36 nightly
Price is $72
$72
Image gallery for Chairú Eco Hotel
Chairú Eco Hotel
3.5 star property
Santa Cruz
9.6/10Exceptional (48 reviews)
25% off
$60 nightly
Price is $120
$120
Image gallery for Hotel LP Santa Cruz Centro
VIP Access
Hotel LP Santa Cruz Centro
3.0 star property
Santa Cruz
8.0/10Very Good (281 reviews)
30% off
$44 nightly
Price is $89
$89
Image gallery for Hotel LP Equipetrol
VIP Access
Hotel LP Equipetrol
3.5 star property
Santa Cruz
8.2/10Very Good (201 reviews)
30% off
$53 nightly
Price is $106
$106
Image gallery for Terranova Suites
Terranova Suites
3.5 star property
Santa Cruz
8.0/10Very Good (90 reviews)
10% off
$52 nightly
Price is $104
$104
Image gallery for Alfonsina Hotel Boutique by Inboccaluppo
Alfonsina Hotel Boutique by Inboccaluppo
3.5 star property
Santa Cruz
9.4/10Exceptional (40 reviews)
10% off
$134 nightly
Price is $268
$268
Image gallery for Hotel Continental Park
Hotel Continental Park
3.0 star property
Santa Cruz
8.8/10Excellent (25 reviews)
10% off
$69 nightly
Price is $138
$138
Image gallery for Hotel Cortez
Hotel Cortez
3.5 star property
Santa Cruz
9.2/10Wonderful (123 reviews)
30% off
$107 nightly
Price is $214
$214
Image gallery for Sun Hotel
VIP Access
Sun Hotel
3.5 star property
Santa Cruz
8.4/10Very Good (331 reviews)
25% off
$90 nightly
Price is $179
$179
Image gallery for Hotel BY Armonia SCZ
Hotel BY Armonia SCZ
3.0 star property
Santa Cruz
8.4/10Very Good (7 reviews)
10% off
$73 nightly
Price is $146
$146
Check out pet-friendly hotels in Santa Cruz
The price is $54
$54
$56 total
Dec 18 - Dec 19
9.6 out of 10, Exceptional, (74)
9.6/10
Exceptional
(74)
The price is $38
$38
$38 total
Dec 22 - Dec 23
The price is $55
$55
$55 total
Dec 18 - Dec 19
9.2 out of 10, Wonderful, (81)
9.2/10
Wonderful
(81)
The price is $140
$140
$140 total
Dec 18 - Dec 19
9.2 out of 10, Wonderful, (122)
9.2/10
Wonderful
(122)
10.0 out of 10, Exceptional, (1)
10/10
Exceptional
(1)
The price is $86
$86
$86 total
Dec 18 - Dec 19
8.4 out of 10, Very Good, (7)
8.4/10
Very Good
(7)
The price is $41
$41
$41 total
Jan 16 - Jan 17, 2026
9.2 out of 10, Wonderful, (34)
9.2/10
Wonderful
(34)
The price is $50
$50
$50 total
Dec 18 - Dec 19
The price is $55
$55
$55 total
Dec 18 - Dec 19
You may also like hotels with spas in Santa Cruz
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (211)
9.0/10
Wonderful
(211)
The price is $111
$111
$111 total
Dec 26 - Dec 27
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (347)
9.0/10
Wonderful
(347)
The price is $125
$125
$125 total
Dec 23 - Dec 24
9.2 out of 10, Wonderful, (81)
9.2/10
Wonderful
(81)
The price is $140
$140
$140 total
Dec 18 - Dec 19
8.8 out of 10, Excellent, (407)
8.8/10
Excellent
(407)
The price is $180
$180
$180 total
Dec 25 - Dec 26
9.2 out of 10, Wonderful, (123)
9.2/10
Wonderful
(123)
The price is $126
$126
$126 total
Dec 24 - Dec 25
The price is $25
$25
$25 total
Dec 18 - Dec 19
7.6 out of 10, Good, (59)
7.6/10
Good
(59)
The price is $63
$63
$63 total
Dec 18 - Dec 19
The price is $54
$54
$56 total
Dec 18 - Dec 19
8.8 out of 10, Excellent, (60)
8.8/10
Excellent
(60)
You can also stay at hotels with a pool in Santa Cruz
The price is $25
$25
$25 total
Dec 18 - Dec 19
The price is $54
$54
$56 total
Dec 18 - Dec 19
Premium Suites Deluxe Aparthotel Equipetrol
Premium Suites Deluxe Aparthotel Equipetrol3.5 star property
Santa Cruz
9.0 out of 10, Wonderful, (81)
9.0/10
Wonderful
(81)
The price is $39
$39
$39 total
Dec 18 - Dec 19
The price is $55
$55
$55 total
Dec 18 - Dec 19
The price is $55
$55
$55 total
Dec 18 - Dec 19
Marriott Santa Cruz de la Sierra Hotel
Marriott Santa Cruz de la Sierra Hotel5.0 star property
Santa Cruz
9.0 out of 10, Wonderful, (211)
9.0/10
Wonderful
(211)
The price is $111
$111
$111 total
Dec 26 - Dec 27
8.0 out of 10, Very Good, (90)
8.0/10
Very Good
(90)
The price is $52
$52
$52 total
Dec 19 - Dec 20
7.6 out of 10, Good, (59)
7.6/10
Good
(59)
The price is $63
$63
$63 total
Dec 18 - Dec 19
10.0 out of 10, Exceptional, (1)
10/10
Exceptional
(1)
The price is $86
$86
$86 total
Dec 18 - Dec 19
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Santa Cruz
Pet friendly
Family friendly
When is the best time to visit Santa Cruz?
When is the best time to visit Santa Cruz?Our prices for hotels in Santa Cruz are cheapest in February
When is the best time to visit Santa Cruz?
When is the best time to visit Santa Cruz?
Our prices for hotels in Santa Cruz are cheapest in February
Price trends for hotels in Santa Cruz
Pricing is based on two traveler single night rates
Currently viewing crowd sizes and weather for December.
Typical weather for Santa Cruz
December
Low crowds
High 31°C / low 22°C. Sunny most days.
View properties in December 31°
December, Low crowds, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
31°
January, Moderate crowds, average high temperature 31 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
29°
February, High crowds, average high temperature 29 degrees Celsius, average low temperature 22 degrees Celsius. Cloudy most days.
22°
29°
March, High crowds, average high temperature 29 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
28°
April, Moderate crowds, average high temperature 28 degrees Celsius, average low temperature 20 degrees Celsius. Sunny most days.
20°
25°
May, Low crowds, average high temperature 25 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
24°
June, Moderate crowds, average high temperature 24 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
25°
July, Moderate crowds, average high temperature 25 degrees Celsius, average low temperature 17 degrees Celsius. Sunny most days.
17°
28°
August, Low crowds, average high temperature 28 degrees Celsius, average low temperature 18 degrees Celsius. Sunny most days.
18°
31°
September, High crowds, average high temperature 31 degrees Celsius, average low temperature 21 degrees Celsius. Sunny most days.
21°
32°
October, High crowds, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
32°
November, Low crowds, average high temperature 32 degrees Celsius, average low temperature 22 degrees Celsius. Sunny most days.
22°
Monthly weather averages (˚C)
Top neighborhoods in Santa Cruz
Top landmarks in Santa Cruz
Santa Cruz Zoo
4.1/5 (23 reviews)
It's feeding time at the zoo! If you want to be reminded of some of the great animals our world is home to, you might want to pay a trip to Santa Cruz Zoo, located 1.7 mi (2.8 km) from central Santa Cruz. If you have fun at Santa Cruz Zoo, you'll love Guembe Biocenter, located nearby.
Learn more about Santa Cruz
Santa Cruz is applauded for its cultural attractions such as Cine Center and Ethno-folkloric Museum.
Check out reviews of Santa Cruz hotels guests love
Chairú Eco Hotel
10/10 Excellent
"Clean room and friendly staff "
Novotel Santa Cruz De La Sierra
10/10 Excellent
"Luxurious hotel,very chic and beautiful."
Hotel LP Santa Cruz Centro
10/10 Excellent
"Clean rooms, well kept facilities and nice staff"
Ibis Santa Cruz DE LA Sierra
10/10 Excellent
"Well kept. Clean, great staff! "
Sun Hotel
10/10 Excellent
"spotless"
Marriott Santa Cruz de la Sierra Hotel
10/10 Excellent
"Muy bien exelente"
HOTEL OSHO
10/10 Excellent
"Hot tub worked well and room was very comfortable! 24 hr market across the street came in handy. The best hotel I've stayed at in Bolivia!"
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
10/10 Excellent
"Everything was absolutely amazing, from the second we arrived to the last day. The service, the room, the property. I always come back to this Hotel time after time. Thank you for all you do to make us feel at home while we’re there "
Camino Real Hotel
10/10 Excellent
"Excellent hotel, I willl always used it in this location "
Frequently asked questions
What hotels do travelers recommend in Santa Cruz?
Ibis Santa Cruz DE LA Sierra, Chairú Eco Hotel and TRYP by Wyndham Santa Cruz are all accommodations that are popular with guests.
Where can I find free parking at my hotel in Santa Cruz?
These hotels offer the perk of free parking: Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel, Hotel LP Equipetrol and Hotel LP Santa Cruz Centro. There are 8 options you may want to check out on our site.
Can I book refundable hotels in Santa Cruz?
If you want the flexibility to change your plans to Santa Cruz, most accommodations offer refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow down the results.
Where can I stay in Santa Cruz if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 24 vacation homes. In addition, you can choose from 183 apartments.
What will the weather in Santa Cruz be like during my trip?
Santa Cruz is a great place to visit to enjoy the sunshine any time of year with an average temp of 70°F.
Why should I book my Santa Cruz accommodation with Hotels.com?
There are lots of reasons to book your Santa Cruz trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.