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Hotels in Southern Illinois
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Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHG
2.5 star property
Effingham
9.4 out of 10, Exceptional, (1000)
9.4/10
Exceptional
(1000)
The price is $104
$104
$116 total
includes taxes & fees
Jan 10 - Jan 11, 2026




Hampton Inn & Suites Effingham
Hampton Inn & Suites Effingham
2.5 star property
Effingham
9.6 out of 10, Exceptional, (680)
9.6/10
Exceptional
(680)
The price is $106
$106
$117 total
includes taxes & fees
Jan 1 - Jan 2, 2026




Comfort Suites Mount Vernon
Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1001)
9.0/10
Wonderful
(1001)
The price is $109
$109
$123 total
includes taxes & fees
Dec 25 - Dec 26




Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1593)
9.6/10
Exceptional
(1593)
The price is $94
$94
$106 total
includes taxes & fees
Dec 28 - Dec 29




SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (908)
8.8/10
Excellent
(908)
The price is $68
$68
$75 total
includes taxes & fees
Dec 31 - Jan 1, 2026




Quality Inn & Suites Metropolis I-24
Quality Inn & Suites Metropolis I-24
2.5 star property
Metropolis
8.0 out of 10, Very Good, (1000)
8.0/10
Very Good
(1000)
The price is $55
$55
$64 total
includes taxes & fees
Jan 11 - Jan 12, 2026




La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1007)
9.2/10
Wonderful
(1007)
The price is $93
$93
$104 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, IL
2.5 star property
Effingham
8.8 out of 10, Excellent, (1002)
8.8/10
Excellent
(1002)
The price is $89
$89
$99 total
includes taxes & fees
Jan 14 - Jan 15, 2026




Baymont by Wyndham Marion
Baymont by Wyndham Marion
2.5 star property
Marion
8.4 out of 10, Very Good, (1076)
8.4/10
Very Good
(1076)
The price is $74
$74
$89 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Super 8 by Wyndham Mt. Vernon IL
Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (1002)
7.8/10
Good
(1002)
The price is $61
$61
$70 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG
2.5 star property
Murphysboro
9.4 out of 10, Exceptional, (512)
9.4/10
Exceptional
(512)
The price is $97
$97
$108 total
includes taxes & fees
Dec 26 - Dec 27




Drury Inn & Suites Marion
Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1006)
9.4/10
Exceptional
(1006)
The price is $65
$65
$78 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Ramada by Wyndham Effingham
Ramada by Wyndham Effingham
3.0 star property
Effingham
7.6 out of 10, Good, (1002)
7.6/10
Good
(1002)
The price is $56
$56
$63 total
includes taxes & fees
Jan 6 - Jan 7, 2026




Laketree Inn And Suites Marion
Laketree Inn And Suites Marion
2.0 star property
Marion
8.0 out of 10, Very Good, (177)
8.0/10
Very Good
(177)
The price is $80
$80
$89 total
includes taxes & fees
Dec 25 - Dec 26




Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
3.5 star property
Metropolis
8.2 out of 10, Very Good, (1001)
8.2/10
Very Good
(1001)
The price is $103
$103
$130 total
includes taxes & fees
Jan 22 - Jan 23, 2026




Best Western Plus Centralia Hotel & Suites
Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (604)
9.6/10
Exceptional
(604)
The price is $121
$121
$135 total
includes taxes & fees
Jan 1 - Jan 2, 2026




Home2 Suites By Hilton Effingham
Home2 Suites By Hilton Effingham
3.0 star property
Effingham
9.6 out of 10, Exceptional, (29)
9.6/10
Exceptional
(29)
The price is $106
$106
$118 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Quality Inn Effingham North
Quality Inn Effingham North
2.5 star property
Effingham
8.4 out of 10, Very Good, (998)
8.4/10
Very Good
(998)
The price is $77
$77
$85 total
includes taxes & fees
Jan 18 - Jan 19, 2026




Comfort Inn & Suites Greenville I-70
Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4 out of 10, Very Good, (416)
8.4/10
Very Good
(416)
The price is $86
$86
$95 total
includes taxes & fees
Dec 28 - Dec 29




Days Inn & Suites by Wyndham Casey
Days Inn & Suites by Wyndham Casey
2.0 star property
Casey
7.4 out of 10, Good, (830)
7.4/10
Good
(830)
The price is $70
$70
$78 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Southern Illinois, IL
Showing deals for:Jan 2 - Jan 4
Image gallery for Red Bud Country Inn

Red Bud Country Inn
2.5 star property
Red Bud
9.0/10Wonderful (51 reviews)
10% off
$77 nightly
Price is $170
$170
Total with taxes and fees Total with taxes and fees
Image gallery for Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination

Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
3.5 star property
Metropolis
8.2/10Very Good (1,001 reviews)
14% off
$169 nightly
Price is $407
$407
Total with taxes and fees Total with taxes and fees
Image gallery for Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL
2.5 star property
Marion
8.6/10Excellent (1,005 reviews)
20% off
$103 nightly
Price is $248
$248
Total with taxes and fees Total with taxes and fees
Image gallery for The Shelby Inn

The Shelby Inn
2.5 star property
Shelbyville
8.8/10Excellent (132 reviews)
10% off
$108 nightly
Price is $236
$236
Total with taxes and fees Total with taxes and fees
Image gallery for Comfort Suites Effingham Central

Comfort Suites Effingham Central
2.5 star property
Effingham
8.8/10Excellent (580 reviews)
20% off
$99 nightly
Price is $222
$222
Total with taxes and fees Total with taxes and fees
Image gallery for The Principal Hotel

VIP Access
The Principal Hotel
3.5 star property
Columbia
9.8/10Exceptional (193 reviews)
10% off
$175 nightly
Price is $388
$388
Total with taxes and fees Total with taxes and fees
Image gallery for Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4/10Very Good (416 reviews)
20% off
$103 nightly
Price is $228
$228
Total with taxes and fees Total with taxes and fees
Image gallery for Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
2.5 star property
Marion
9.4/10Exceptional (1,002 reviews)
20% off
$109 nightly
Price is $261
$261
Total with taxes and fees Total with taxes and fees
Image gallery for Comfort Suites Mattoon East

Comfort Suites Mattoon East
2.5 star property
Mattoon
8.8/10Excellent (880 reviews)
20% off
$100 nightly
Price is $223
$223
Total with taxes and fees Total with taxes and fees
Image gallery for Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL
2.5 star property
Effingham
8.8/10Excellent (1,002 reviews)
20% off
$93 nightly
Price is $206
$206
Total with taxes and fees Total with taxes and fees
Image gallery for Clarion Pointe Mattoon near University

Clarion Pointe Mattoon near University
2.5 star property
Mattoon
8.4/10Very Good (867 reviews)
20% off
$80 nightly
Price is $178
$178
Total with taxes and fees Total with taxes and fees
Image gallery for Country View Inn & Suites

Country View Inn & Suites
2.5 star property
Robinson
9.2/10Wonderful (280 reviews)
$131 nightly
Price is $292
$292
Total with taxes and fees Total with taxes and fees
Image gallery for Quality Inn & Suites Mattoon South

Quality Inn & Suites Mattoon South
2.5 star property
Mattoon
8.6/10Excellent (782 reviews)
20% off
$89 nightly
Price is $198
$198
Total with taxes and fees Total with taxes and fees
Image gallery for Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
Edwardsville
8.4/10Very Good (808 reviews)
20% off
$103 nightly
Price is $237
$237
Total with taxes and fees Total with taxes and fees
Image gallery for Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.4/10Very Good (1,000 reviews)
20% off
$63 nightly
Price is $138
$138
Total with taxes and fees Total with taxes and fees
Image gallery for Comfort Inn Collinsville near St. Louis

Comfort Inn Collinsville near St. Louis
2.5 star property
Collinsville
8.6/10Excellent (885 reviews)
20% off
$98 nightly
Price is $224
$224
Total with taxes and fees Total with taxes and fees
Image gallery for Quality Inn Effingham North

Quality Inn Effingham North
2.5 star property
Effingham
8.4/10Very Good (998 reviews)
20% off
$82 nightly
Price is $181
$181
Total with taxes and fees Total with taxes and fees
Image gallery for Country Inn & Suites by Radisson, Fairview Heights, IL

Country Inn & Suites by Radisson, Fairview Heights, IL
3.0 star property
Fairview Heights
8.0/10Very Good (48 reviews)
20% off
$84 nightly
Price is $190
$190
Total with taxes and fees Total with taxes and fees
Image gallery for Super 8 by Wyndham Troy IL/St. Louis Area

Super 8 by Wyndham Troy IL/St. Louis Area
2.0 star property
Troy
8.0/10Very Good (1,000 reviews)
15% off
$64 nightly
Price is $142
$142
Total with taxes and fees Total with taxes and fees
Budget hotels in Southern Illinois and vicinity




7.0 out of 10, Good, (884)
7.0/10
Good
(884)
The price is $40
$40
$46 total
includes taxes & fees
Dec 28 - Dec 29




7.2 out of 10, Good, (1002)
7.2/10
Good
(1002)
The price is $43
$43
$49 total
includes taxes & fees
Jan 4 - Jan 5, 2026




7.4 out of 10, Good, (1002)
7.4/10
Good
(1002)
The price is $45
$45
$52 total
includes taxes & fees
Jan 1 - Jan 2, 2026




8.0 out of 10, Very Good, (1000)
8.0/10
Very Good
(1000)
The price is $55
$55
$64 total
includes taxes & fees
Jan 11 - Jan 12, 2026




7.4 out of 10, Good, (1000)
7.4/10
Good
(1000)
The price is $55
$55
$63 total
includes taxes & fees
Dec 29 - Dec 30




7.2 out of 10, Good, (937)
7.2/10
Good
(937)
The price is $61
$61
$70 total
includes taxes & fees
Dec 28 - Dec 29




7.6 out of 10, Good, (1002)
7.6/10
Good
(1002)
The price is $56
$56
$63 total
includes taxes & fees
Jan 6 - Jan 7, 2026




7.8 out of 10, Good, (577)
7.8/10
Good
(577)
The price is $59
$59
$66 total
includes taxes & fees
Dec 30 - Dec 31




Days Inn by Wyndham Collinsville/St. Louis
Days Inn by Wyndham Collinsville/St. Louis2.5 star property
Eastport
7.2 out of 10, Good, (1006)
7.2/10
Good
(1006)
The price is $59
$59
$67 total
includes taxes & fees
Dec 28 - Dec 29




7.4 out of 10, Good, (1007)
7.4/10
Good
(1007)
The price is $59
$59
$70 total
includes taxes & fees
Jan 21 - Jan 22, 2026




7.6 out of 10, Good, (1002)
7.6/10
Good
(1002)
The price is $60
$60
$67 total
includes taxes & fees
Dec 28 - Dec 29




7.4 out of 10, Good, (703)
7.4/10
Good
(703)
The price is $59
$59
$66 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Super 8 by Wyndham Troy IL/St. Louis Area
Super 8 by Wyndham Troy IL/St. Louis Area2.0 star property
Troy
8.0 out of 10, Very Good, (1000)
8.0/10
Very Good
(1000)
The price is $64
$64
$71 total
includes taxes & fees
Dec 30 - Dec 31




8.2 out of 10, Very Good, (486)
8.2/10
Very Good
(486)
The price is $64
$64
$68 total
includes taxes & fees
Dec 30 - Dec 31




7.8 out of 10, Good, (810)
7.8/10
Good
(810)
The price is $64
$64
$69 total
includes taxes & fees
Dec 28 - Dec 29




7.2 out of 10, Good, (496)
7.2/10
Good
(496)
The price is $64
$64
$70 total
includes taxes & fees
Jan 6 - Jan 7, 2026




9.4 out of 10, Exceptional, (1006)
9.4/10
Exceptional
(1006)
The price is $65
$65
$78 total
includes taxes & fees
Jan 2 - Jan 3, 2026




7.8 out of 10, Good, (1002)
7.8/10
Good
(1002)
The price is $61
$61
$70 total
includes taxes & fees
Jan 4 - Jan 5, 2026




Quality Inn & Suites Vandalia near I-70 and Hwy 51
Quality Inn & Suites Vandalia near I-70 and Hwy 512.5 star property
Vandalia
8.4 out of 10, Very Good, (1000)
8.4/10
Very Good
(1000)
The price is $67
$67
$73 total
includes taxes & fees
Dec 28 - Dec 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check out pet-friendly hotels in Southern Illinois




9.6 out of 10, Exceptional, (680)
9.6/10
Exceptional
(680)
The price is $106
$106
$117 total
includes taxes & fees
Jan 1 - Jan 2, 2026




SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend Lake2.5 star property
Whittington
8.8 out of 10, Excellent, (908)
8.8/10
Excellent
(908)
The price is $68
$68
$75 total
includes taxes & fees
Dec 31 - Jan 1, 2026




9.0 out of 10, Wonderful, (1001)
9.0/10
Wonderful
(1001)
The price is $109
$109
$123 total
includes taxes & fees
Dec 25 - Dec 26




9.6 out of 10, Exceptional, (1593)
9.6/10
Exceptional
(1593)
The price is $94
$94
$106 total
includes taxes & fees
Dec 28 - Dec 29




8.0 out of 10, Very Good, (177)
8.0/10
Very Good
(177)
The price is $80
$80
$89 total
includes taxes & fees
Dec 25 - Dec 26




9.4 out of 10, Exceptional, (1006)
9.4/10
Exceptional
(1006)
The price is $65
$65
$78 total
includes taxes & fees
Jan 2 - Jan 3, 2026




Best Western Plus Centralia Hotel & Suites
Best Western Plus Centralia Hotel & Suites2.5 star property
Centralia
9.6 out of 10, Exceptional, (604)
9.6/10
Exceptional
(604)
The price is $121
$121
$135 total
includes taxes & fees
Jan 1 - Jan 2, 2026




9.6 out of 10, Exceptional, (804)
9.6/10
Exceptional
(804)
The price is $99
$99
$107 total
includes taxes & fees
Dec 28 - Dec 29




Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Holiday Inn Express Hotel & Suites Marion Northeast by IHG2.5 star property
Marion
9.0 out of 10, Wonderful, (928)
9.0/10
Wonderful
(928)
The price is $105
$105
$126 total
includes taxes & fees
Jan 4 - Jan 5, 2026




La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham Effingham3.0 star property
Effingham
9.2 out of 10, Wonderful, (1007)
9.2/10
Wonderful
(1007)
The price is $93
$93
$104 total
includes taxes & fees
Jan 4 - Jan 5, 2026
You may also like hotels with hot tubs in Southern Illinois




9.0 out of 10, Wonderful, (1001)
9.0/10
Wonderful
(1001)
The price is $109
$109
$123 total
includes taxes & fees
Dec 25 - Dec 26




9.6 out of 10, Exceptional, (1593)
9.6/10
Exceptional
(1593)
The price is $94
$94
$106 total
includes taxes & fees
Dec 28 - Dec 29




Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHG2.5 star property
Effingham
9.4 out of 10, Exceptional, (1000)
9.4/10
Exceptional
(1000)
The price is $104
$104
$116 total
includes taxes & fees
Jan 10 - Jan 11, 2026




Quality Inn & Suites Vandalia near I-70 and Hwy 51
Quality Inn & Suites Vandalia near I-70 and Hwy 512.5 star property
Vandalia
8.4 out of 10, Very Good, (1000)
8.4/10
Very Good
(1000)
The price is $67
$67
$73 total
includes taxes & fees
Dec 28 - Dec 29




Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake2.5 star property
Mount Vernon
8.8 out of 10, Excellent, (684)
8.8/10
Excellent
(684)
The price is $100
$100
$113 total
includes taxes & fees
Jan 2 - Jan 3, 2026




9.4 out of 10, Exceptional, (1002)
9.4/10
Exceptional
(1002)
The price is $108
$108
$130 total
includes taxes & fees
Jan 6 - Jan 7, 2026




9.2 out of 10, Wonderful, (1010)
9.2/10
Wonderful
(1010)
The price is $84
$84
$94 total
includes taxes & fees
Jan 6 - Jan 7, 2026




7.2 out of 10, Good, (447)
7.2/10
Good
(447)
The price is $61
$61
$67 total
includes taxes & fees
Jan 2 - Jan 3, 2026




9.4 out of 10, Exceptional, (1006)
9.4/10
Exceptional
(1006)
The price is $65
$65
$78 total
includes taxes & fees
Jan 2 - Jan 3, 2026




9.4 out of 10, Exceptional, (388)
9.4/10
Exceptional
(388)
The price is $125
$125
$139 total
includes taxes & fees
Dec 25 - Dec 26
You can also stay at hotels with a pool in Southern Illinois




Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHG2.5 star property
Effingham
9.4 out of 10, Exceptional, (1000)
9.4/10
Exceptional
(1000)
The price is $104
$104
$116 total
includes taxes & fees
Jan 10 - Jan 11, 2026




9.6 out of 10, Exceptional, (680)
9.6/10
Exceptional
(680)
The price is $106
$106
$117 total
includes taxes & fees
Jan 1 - Jan 2, 2026




9.6 out of 10, Exceptional, (1593)
9.6/10
Exceptional
(1593)
The price is $94
$94
$106 total
includes taxes & fees
Dec 28 - Dec 29




9.4 out of 10, Exceptional, (1006)
9.4/10
Exceptional
(1006)
The price is $65
$65
$78 total
includes taxes & fees
Jan 2 - Jan 3, 2026




9.0 out of 10, Wonderful, (1001)
9.0/10
Wonderful
(1001)
The price is $109
$109
$123 total
includes taxes & fees
Dec 25 - Dec 26




La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham Effingham3.0 star property
Effingham
9.2 out of 10, Wonderful, (1007)
9.2/10
Wonderful
(1007)
The price is $93
$93
$104 total
includes taxes & fees
Jan 4 - Jan 5, 2026




8.4 out of 10, Very Good, (1076)
8.4/10
Very Good
(1076)
The price is $74
$74
$89 total
includes taxes & fees
Jan 2 - Jan 3, 2026




8.0 out of 10, Very Good, (1000)
8.0/10
Very Good
(1000)
The price is $55
$55
$64 total
includes taxes & fees
Jan 11 - Jan 12, 2026




Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, IL2.5 star property
Effingham
8.8 out of 10, Excellent, (1002)
8.8/10
Excellent
(1002)
The price is $89
$89
$99 total
includes taxes & fees
Jan 14 - Jan 15, 2026




Holiday Inn Carbondale-Conference Center by IHG
Holiday Inn Carbondale-Conference Center by IHG3.0 star property
Carbondale
8.8 out of 10, Excellent, (645)
8.8/10
Excellent
(645)
The price is $114
$114
$131 total
includes taxes & fees
Jan 21 - Jan 22, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Go beyond your typical stay in Southern Illinois
Pet friendly
Family friendly
Apartment
Cottage
Top landmarks in Southern Illinois
Learn more about Southern Illinois
Southern Illinois is applauded for its entertainment and live music with such cultural attractions as Effingham Performance Center and Mid America Motorworks, My Garage Museum. Visitors highlight this family-friendly city's sports while sights include Jefferson County Fairgrounds and Salem Fairgrounds.

Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau
Check out reviews of Southern Illinois hotels guests love

Drury Plaza Hotel Mt. Vernon
10/10 Excellent
"Nice and clean place. Friendly staff."

Drury Inn & Suites St. Louis O'Fallon, IL
10/10 Excellent
"Everyone was very friendly and professional. The room was comfortable and had sufficient outlets for charging."

Drury Inn & Suites St. Louis Fairview Heights
10/10 Excellent
"Breakfast food was not very hot. Everything else was great."

Comfort Suites Mount Vernon
10/10 Excellent
"Check in was quick, staff was friendly and helpful, room was very nice and clean."

Red Lion Inn & Suites Pontoon Beach
10/10 Excellent
"Everything was great!"

Holiday Inn Express Troy by IHG
10/10 Excellent
"Room was clean, staff were nice and efficient and the coffee in the lobby was great. Coffee beans were ground and brewed individually for each cup!"

Quality Inn O'Fallon IL - St. Louis
10/10 Excellent
"Rooms are always great. The price is excellent and the staff have always been very friendly. Each time we visit home Illinois we stay there. "

The Principal Hotel
10/10 Excellent
"Wonderful experience-luxury rooms, great dining, amazing staff! Clean and themed wel!! "

Drury Inn & Suites Marion
10/10 Excellent
"Clean room, good food"
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