Hotels in South Carolina Lowcountry

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Mar 27 - Mar 28
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Apr 4 - Apr 6

Where to stay in South Carolina Lowcountry?

Red Roof Inn Yemassee
Lobby

Red Roof Inn Yemassee

2.0 star property
7.4 out of 10, Good, (531)
The price is $74
$81 total
includes taxes & fees
Mar 30 - Mar 31
Red Roof Inn Yemassee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in South Carolina Lowcountry, SC

Showing deals for:Apr 4 - Apr 6

Image gallery for Seawatch at Island Club

Aerial view

Seawatch at Island Club

3.0 star property
Hilton Head Island
9.2/10Wonderful (21 reviews)
26% off
Price is $369
per night
$812 total
includes taxes & fees
Seawatch at Island Club

Top neighborhoods in South Carolina Lowcountry

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Sea Pines

Hilton Head Island's Sea Pines neighborhood has a host of places to visit such as Atlantic Dunes by Davis Love III and Harbour Town Golf Links.

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Sea Pines

Top landmarks in South Carolina Lowcountry

Marine Corps Recruit Depot Parris Island

Marine Corps Recruit Depot Parris Island

Marine Corps Recruit Depot Parris Island is worth a visit, located 0.6 mi (0.9 km) from central Parris Island. Hotels.com travelers also say the area is family-friendly and has lots of nice beaches.

See properties in Marine Corps Recruit Depot Parris Island
Marine Corps Recruit Depot Parris Island

Learn more about South Carolina Lowcountry

South Carolina Lowcountry is applauded for its cultural attractions such as Parris Island Museum and Highway 21 Drive-In Theater.

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Hilton Head featuring heritage architecture
Photo by Hilton Head Island Visitor & Convention Bureau
Open Photo by Hilton Head Island Visitor & Convention Bureau

Frequently asked questions

Can I book refundable hotels in South Carolina Lowcountry?
If you want the flexibility to change your travel plans to South Carolina Lowcountry, most hotels provide refundable* bookable rates. You can find these properties by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay in South Carolina Lowcountry if I want a vacation home instead of a hotel?
If you want to find a good alternative to a hotel, review our selection of 4188 vacation homes. In addition, there are 225 apartments and 3043 condos.
Why should I book my South Carolina Lowcountry accommodation with Hotels.com?
There are lots of reasons to book your South Carolina Lowcountry trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.